diabetic ketoacidosis and hyperglycemic hyperosmolar state wolfsdorf

 

 

 

 

PATHOPHYSIOLOGY COURSE - ENDOCRINE MODULE Hyperglycemic Crises in Diabetes Mellitus, Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State Abbas E. Kitabchi, Ph.D M.D. Monday, December 14, 2009 Background. Hyperosmolar hyperglycemic state (HHS) is one of two serious metabolic derangements that occurs in patients with diabetes mellitus (DM). [1] It is a life-threatening emergency that, although less common than its counterpart, diabetic ketoacidosis (DKA) J. I. Wolfsdorf, J. Allgrove, M. E. Craig et al Diabetic ketoacidosis and hyperglycemic hyperosmolar state, Pediatric Diabetes, vol. 15, no. 20, pp. 154179, 2014. Hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA) represent two distinct metabolic derangements manifested by insulin deficiency and severe hyperglycemia. Hyperosmolar hyperglycemic state (HHS) is a complication of diabetes mellitus in which high blood sugar results in high osmolarity without significant ketoacidosis. Symptoms include signs of dehydration, weakness, legs cramps, trouble seeing, and an altered level of consciousness.

Hyperglycemic crises in diabetes mellitus: diabetic ketoacidosis and hyperglycemic hyperosmolar state.29 Quinn M, Fleischman A, Rosner B, Nigrin DJ, Wolfsdorf JI. Characteristics at diagnosis of type 1 diabetes in children younger than 6 years. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS, also known as hyperosmotic hyperglycemic nonketotic state [HHNK]) are Continue. Modified from Glaser NS: Pediatric diabetic ketoacidosis and hyperglycemic hyperosmolar state.(From Wolfsdorf J, Glaser N, Sperling MA: Diabetic ketoacidosis in infants, children, and adolescents: a consensus statement from the American Diabetes Association, Diabetes Care 29[5] Hyperglycemic crises in diabetes mellitus: diabetic ketoacidosis and hyperglycemic hyperosmolar state. Endocrinology and metabolism clinics of North America 2006 35:725-751, viii.J Pediatr 2004 145:164-171. Krane EJ, Rockoff MA, Wallman JK, Wolfsdorf JI. [1] Kitabchi AE, Umpierrez GE, Murphy MB, et al. Management of hyperglycemic crises in patients with diabetes.toolbestpractice.com [4] Wolfsdorf JI, Allgrove J, Craig ME, et al International Society for Pediatric andDiabetic ketoacidosis and hyperglycemic hyperosmolar state. Diabetic ketoacidosis and hyperglycemic hyperosmolar state.

6. Quinn M, Fleischman A, Rosner B, Nigrin DJ, Wolfsdorf JI. Characteristics at diagnosis of type 1 diabetes in children younger than 6 years. References. Hyperglycemic hyperosmolar state in adults.Wolfsdorf J, et al. ISPAD Clinical Practice Consensus Guidelines 2014. Diabetic ketoacidosis and hyperglycemic hyperosmolar state. Abstract. DIABETIC KETOACIDOSIS AND THE HYPERGLYCEMIC hyperosmolar state are the most serious complications of diabetic decompensation and remain associated with excess mortality. hyperglycemia Anion gap acidosis ketonemia/ketonuria Dehydration Potassium deficits.Hyperglycemic Hyperosmolar State (HHS). similar to DKA without the ketones Has severely high levels of BG (800 mg/dL). Upcoming: March 1, 2018 12:00 p.m. — 1:00 p.m. Billings Auditorium—P117. Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State in Children and Adolescents. Jospeh Wolfsdorf, MD Director, Diabetes Program Boston Childrens Hospital PowerPoint Slideshow about Diabetic Ketoacidosis (DKA) amp Hyperglycemic Hyperosmolar State (HHS) - astra. Download Now An Image/Link below is provided (as is) to download presentation. Diabetic ketoacidosis. Hyperglycemic hyperosmolar nonketotic coma.Periods of illness can significantly raise blood glucose levels, which could lead to Hyperosmolar Hyperglycaemic State (HHS) if medication is not sufficient to lower sugar levels. 22. Maletkovic J, Drexler A. Diabetic ketoacidosis and hyperglycemic hyperosmolar state.56. Wolfsdorf J, Glaser N, Sperling MA. Diabetic ketoacidosis in infants, children, and adolescents: A consensus statement from the American Diabetes Association. References: Wolfsdorf JI, Allgrove J, Craig ME et al. International Society for Pediatric and Adolescent Diabetes. ISPAD Clinical Practice Consensus Guidelines 2014. Diabetic ketoacidosis and hyperglycemic hyperosmolar state. Left untreated, diabetic ketoacidosis can lead to a diabetic coma and be life-threatening. Hyperglycemic hyperosmolar syndrome.Accessed March 24, 2015. Kitabchi AE, et al. Diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults: Treatment. http Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state.A dose-defining insulin algorithm for attainment and maintenance of glycemic targets during therapy of hyperglycemic crises. Diabetes Manage. PURPOSE OF REVIEW: Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are diabetic emergencies that cause high morbidity and mortality. Their treatment differs in the UK and USA. Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar nonketotic syndrome (HHNS) are life-threatening acute metabolic complications of diabetes mellitus. Although there are some important differences, the pathophysiology, the presenting clinical challenge Diabetic Ketoacidosis. Gastroenteritis Hyperosmolar. hyperglycemic state Myocardial infarction14 Pancreatitis18 Starvation ketosis14.30. Wolfsdorf J, Craig ME, Daneman D, et al. Diabetic ketoacidosis in children and adolescents with diabetes. Detailed management of Diabetic Ketoacidosis, Hyperglycemic Hyperosmolar state and Hypoglycaemia are discussed.The effective serum osmolality is calculated as follows: Diabetic Coma: Diabetic Ketoacidosis, Hyperglycemic Hyperosmolar State and Hypoglycaemia. Michael Gonzalez-Campoy, J Robertson, RP 1996, Diabetic ketoacidosis and hyperosmolar nonketotic state: Gaining control over extreme hyperglycemic complications Postgraduate Medicine, vol 99, no. 6, pp. 143-152. Management of decompensated diabetes diabetic, diabetic ketoacidosis dka and hyperglycemic hyperosmolar state hhs represent two extremes in the spectrum of marked decompensation of diabetes mellitus 12 61 dka. Authors: Wolfsdorf, Joseph I Allgrove, Jeremy Craig, Maria E Edge, Julie Glaser, Nicole Jain, Vandana Lee, Warren WR Mungai, Lucy NW Rosenbloom, Arlan L Sperling, Mark A Hanas, Ragnar. Source: Pediatric Diabetes, Volume 15, Supplement 20, 1 September 2014, pp. 154-179(26).

Diabetic ketoacidosis (DKA) is the presence of ketoacidosis hypergylcemia. Hyperosmolar hyperglycemic state (HHS) is characterized by more severe hyperglycemia but w/out ketoacidosis. Wolfsdorf JI, Allgrove J, Craig ME, Edge J, Glaser N, Jain V, Lee WWR, Mungai LNW, Rosenbloom AL, Sperling MA, Hanas R. A Consensus Statement from the International Society for Pediatric and Adolescent Diabetes: Diabetic ketoacidosis and hyperglycemic hyperosmolar state. Diabetic ketoacidosis Hyperosmolar nonketotic hyperglycaemia Hypoglycaemia Lactic acidosis Other causes, like stroke, postictal (after hypo?), cerebral trauma, alcohol intoxication, drug overdose, etc. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS, also called hyperosmotic hyperglycemic nonketotic state) are two of the most serious acute complications of diabetes.Professor of Medicine. Harvard Medical School. Joseph I Wolfsdorf, MB, BCh. Wolfsdorf J, Glaser N, Sperling MA (2006) Diabetic ketoacidosis in infants, children, and adolescents: a consensus statement fromCite this chapter as: Woode D.E Kitabchi A.E. (2011) Hyperglycemic Crises in Diabetes Mellitus: Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State. 1 What is diabetic ketoacidosis (DKA)?9 How does the hyperosmolar hyperglycemic state (HHS) differ from DKA? HHS also is characterized by profound hyperglycemia but without ketoacidosis. Diabetic ketoacidosis and hyperglycemic hyperosmolar state (2014) Joseph I Wolfsdorf et al. Hypoglycemic effect of exo- and endo-biopolymers produced by submerged mycelial culture of ganoderma lucidum in streptozotocin-induced diabetic rats (2004) Yang Byung-keun et al. Resumo. Diabetic ketoacidosis (DKA) and the hyperglycemic hyperosmolar state (HHS) are potentially fatal hyperglycemic crises that occur as acute complications of uncontrolled diabetes mellitus. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are the most life threatening acute complications of diabetes mellitus. DKA is more common in younger patients with type 1 diabetes, but can also occur in type 2 diabetes. Hyperglycemic hyperosmolar state insulin titration iii. Adjust insulin infusion rate as needed to achieve a decrease in serum glucose of 50-75mg/dl per hour. Diabetic ketoacidosis and hyperglycemic hyperosmolar state (general features/diagnosis) 1/3. Pediatric Diabetes 2014 .Wolfsdorf et al. 79). As the plasma glucose concentration decreases after administering fluid and insulin.6)/5. therefore.Hyperglycemic crises in diabetes mellitus: diabetic ketoacidosis and hyperglycemic hyperosmolar state. Banasiak KJ. de Beaufort C et al. Diabetic Ketoacidosis in Children. Hyperglycemic Crises in Adult Patients with Diabetes.Project: Ghana Emergency Medicine Collaborative Document Title: Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State (2012) Author(s): Jennifer N. (1) Wolfsdorf JI et al. Diabetic ketoacidosis and hyperglycemic hyperosmolar state.Hyperosmolar hyperglycemic state: a historic review of the clinical presentation, diagnosis, and treatment. Diabetes Care. Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state. Jean-Louis Chiasson, Nahla Aris-Jilwan, Raphal Blanger, Sylvie Bertrand, Hugues Beauregard, Jean-Marie ko, Hlne Fournier, Jana Havrankova. Hyperglycemic Crises: Diabetic Ketoacidosis (DKA), And Hyperglycemic Hyperosmolar State (HHS).Hyperglycemic crises in patients with diabetes: diabetic ketoacidosis (dka), and hyperglycemic hyperosmolar state (HHS). in patients with diabetes. Diabetes Care 200124:131153 5. Wolfsdorf J, Glaser N, Sperling MA.Diabetic ketoacidosis and the hyperglycemic hyperosmolar nonke-totic state. In Joslins Diabetes Mellitus. Diabetic ketoacidosis and hyperglycemic hyperosmolar state. Wolfsdorf JI1, Allgrove J, Craig ME, Edge J, Glaser N, Jain V, Lee WW, Mungai LN, Rosenbloom AL, Sperling MA, Hanas R International Society for Pediatric and Adolescent Diabetes. Joseph Wolfsdorf, Maria E. Craig, Denis Daneman, David Dunger, Julie Edge, Warren Lee, Arlan Rosenbloom, Mark Sperling, and Ragnar Hanas.Hyperglycemic crises in diabetes mellitus: diabetic ketoacidosis and hyper-glycemic hyperosmolar state. Abstract. Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are the most serious and life-threatening hyperglycemic emergencies in diabetes. Diabetic hyperglycemic hyperosmolar syndrome (HHS) is a complication of type 2 diabetes.Buildup of ketones in the body (ketoacidosis) may also occur. But it is unusual and is often mild compared with diabetic ketoacidosis. [[Video:I Was Sinking Into a Diabetic Coma|thumb|300px|right|I Was Sinking Into a Diabetic Coma - Hyperosmolar nonketotic diabetic coma ]]. Hyperosmolar hyperglycemic state (HHS) is one of two serious metabolic derangements that occurs in patients with diabetes mellitus and can be a

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